Polio's pretty special because once you get an eradication, you no longer have to spend money on it; it's just there as a gift for the rest of time.

SPAM is taking e-mail, which is a wonderful tool, and exploiting the idea that it's very inexpensive to send mail.

If somebody is working on a new medicine, computer science helps us model those things. We have a whole group here in Seattle called the Institute for Disease Modelling that is a mix of computer science and math-type people, and the progress we're making in polio or plans for malaria or really driven by their deep insights.

In fact, that's where my vision of the coming digital opportunity is somewhat different from other people's. I divide it into three parts. One is the office. That's the one I'm most excited about and is the most concrete.

If your culture doesn't like geeks, you are in real trouble.

If the 1980s were about quality and the 1990s were about reengineering, then the 2000s will be about velocity.

Ridiculous sums of money can be confusing.