As we have taken diarrhea and pneumonia down, even malaria down quite a bit, the portion of the days that are very early in that 5 years - the first month, the first day - it's about half now. Yet that's the part we understand the least.

A first-generation fortune is the most likely to be given away, but once a fortune is inherited it's less likely that a very high percentage will go back to society.

Creating a piece of software is always complicated because you're doing something new. If you just wanted something that had been done before you'd just use that old piece of software. So there are no repetitive tasks.

I believe it’s not only possible to eradicate malaria; I believe it’s necessary. Ultimately, the cost of controlling it endlessly is not sustainable. The only way to stop this disease is to end it forever.

Exposure from a young age to the realities of the world is a super-big thing.

America's high schools are obsolete. By obsolete, I don't just mean that they're broken, flawed, or underfunded, though a case could be made for every one of those points. By obsolete, I mean our high schools-even when they're working as designed-cannot teach all our students what they need to know today.

We're at the point now where the challenge isn't how to communicate effectively with e-mail; it's ensuring that you spend your time on the e-mail that matters most.