Software innovation, like almost every other kind of innovation, requires the ability to collaborate and share ideas with other people, and to sit down and talk with customers and get their feedback and understand their needs.

The only definition by which Americas best days are behind it is on a purely relative basis.

We are seeing smarter philanthropy, more philanthropy, and that's true world wide. So it's kind of a movement that has a lot of accomplishments, even though as a percentage of the economy, it's still only a few per cent.

Intellectual property has the shelf life of a banana.

The media covers what’s new – and millions of people dying is nothing new. So it stays in the background, where it’s easier to ignore. But even when we do see it or read about it, it’s difficult to keep our eyes on the problem. It’s hard to look at suffering if the situation is so complex that we don’t know how to help. And so we look away.

If you withdraw the incredible focus on polio, it will spread back, and in poor countries you'll get something like 100,000 cases a year. So by being very intense and getting the cases down to zero, what you do is you avoid all the future cases.

We're very enthused about the idea that in the third trimester we actually give the mother a vaccine and her antibodies, the protective things that the immune system makes, actually pass through to the baby, both when the baby is born, and through the mother's milk. Because the baby's immune system is actually not very strong for that first few months, using the mother's immune system to do this - it's a very exciting idea and something that we're investing heavily in.