Success isn´t guaranteed, but failure is certain if you aren´t truly emotionally invested in your work.

Even the simplest tools can empower people to do great things.

I never even graduated college. I never finished learning, as it were, and I have a psychological need to be in a learning environment at all times.

Doing startups is all about making mistakes.

A Twitter update is simple and fast and gets the information and news, and it spreads it very quickly, and it can contain links so you can then link to this whole context of information.

When you think about email or IMing, why aren't you writing back? I can see your avatar, I know you're online, why aren't you writing me back? But with Twitter, everybody sends their responses to Twitter, and Twitter then sends them out to everyone. So there's not this constant connection. You can be hyperconnected, then you can take a break for a couple days and it's fine.

This idea that the open exchange of information can have a positive global impact is being proven over and over again around the world nearly on a daily basis - and for Secretary Clinton to recognize that, I think, is a huge step.