In fiction the story lives the more everyone comes to life, the more each character seems to exist in his or her own right.

If an artwork never gets any attention from anybody, then obviously it's got problems. If it gains attention from a very small elite, then it's presumably doing something. Finnegans Wake gets a lot of attention from certain people who become passionate about it, who are usually very good readers in general. Although - I often talk about costs and benefits - it seems to me the costs of reading Finnegans Wake are not worth the benefits, however many there may be. And it's the same with the more arcane among poets, Zukofsky and so on.

Everything is humanities. The sciences are a form of the humanities. They involve traditions of inquiry; they involve social engagement with ideas. They do not happen with a naked brain going out and encountering a nonhuman world. And the better we understand ourselves, the better we can do science, as well. So I don't see them - the sciences and the humanities - as being at all different.

Scientists, to give them credit, do not think of the humanities in a negative way. It's the bureaucrats who want to cut costs who think, Well, here's something that's not booming at the moment, let's slash it.

I think that's an important part of art in general. Especially in literature, in stories, we play with eventualities that may put us through a lot of intense negative feelings - say, in horror films or tragedies as intense as King Lear - but we come out feeling richer. We've lived to the fullest, we've tested ourselves in these environments.

Perhaps the most demanding trick in all of art is to know ways that are going to capture the attention of an audience right now, and yet to also hold an audience hundreds or thousands of years into the future in circumstances you just cannot imagine. You've got to go very deep into human nature to do that.

Any artist who really engages with the problems in their medium at that moment and tries to deepen the problems is likely to discover new problems, new possibilities that will excite audiences and continue to excite them.