I am glad that people are trying to have a rational conversation about drugs.

You have rappers saying "stay off drugs, go to school" - empty verbal behavior. I think all of this became institutionalized in the early '90s. And it's become more and more solidified, more and more entrenched.

People rarely die from heroin alone, it's the combination that's deadly. Maybe we should blast that out as a public health education message. That way at least we're keeping people safe.

Much of the early work focused on dopamine and we were really looking for rewarding sorts of effects and sure enough, we only found that. But you can destroy the main dopamine-producing structures of the brain and you can still get an animal to self-administer drugs like cocaine.

I am glad that people are trying to have a rational conversation about drugs.

Crack in the early 1980s or mid 1980s I'm sorry is that one of the worst myth is that one hit and you're addicted for life. We saw that in 1980s and we're seeing it again with methamphetamine today, one hit and you're addicted and it simply not true, addiction requires work not the people should go out and experiment or do these themselves but the fact is that's a myth and the concern is that, it's dangerous because when people perpetuates that myths and then when young people are people actually try methamphetamine or crack cocaine and find that, that doesn't happen to them.

I have three boys. And I wanted to make sure it connected with them and then those guys who grew up like me, in environments like me.And then I knew something about science that your New York Times reader would be interested in. So I was thinking about it in multiple ways: I'll connect with the people who grew up like me first, and then the New York Times reader will be interested in the science because it's so good and they want to be "in the know."