I am glad that people are trying to have a rational conversation about drugs.

Dopamine makes up less than one percent of the brain's neurotransmitters. It's a small portion. Dopamine is released when people are happy, angry, stressed. So it's really hard to call this specific neurotransmitter "the pleasure neurotransmitter."

I think about my cocaine use. I liked it. I thought it was a great drug. But I knew that if I was doing that almost exclusively, I wouldn't be able to continue to also have significant others and a wide range of other things. And I wasn't special. A number of people, including the people I was doing cocaine with, also behaved the same way.

When you have the national narrative being "crack is awful and black people are using it," why go against that narrative when you want to get that publication in The New York Times or wherever? It encourages people to play right into it.

Your decision to place your law enforcement resources in these communities is racism, but nobody has called people out on this. The law itself is not racist. But people's decision about where we're going to place our efforts, who we're going to prosecute, who we're not going to prosecute, is racism. And nobody's calling them on it.

You have rappers saying "stay off drugs, go to school" - empty verbal behavior. I think all of this became institutionalized in the early '90s. And it's become more and more solidified, more and more entrenched.

Take crack cocaine. Particularly in the early days of the policy, ninety percent of the people being arrested were black, even though they didn't use the drug at higher rates and even though their numbers in the general population are so low. How could that be? The thing is, you place all your resources in communities of color. And if you do that, you're going to arrest black people.