I've had investigations of my lab because people didn't like what I had to say. And when you have investigations and you're doing research, you're shut down for a while. You have to start all over again. So that's one area where I paid a high price.

Our ability to study the brain has been limited because of our tools and our tools have only allowed us to look at one neurotransmitter and we haven't looked so much into co-localization and co-release of transmitters. Our thinking is hampered by our tools.

People rarely die from heroin alone, it's the combination that's deadly. Maybe we should blast that out as a public health education message. That way at least we're keeping people safe.

Looking at the data and at my drug use and evaluating it carefully just let me see that I wasn't special, but my drug use challenged what I thought about cocaine. Because I would accept when I would say, "What happened to that person?" and someone would say, "They started using cocaine...they went downhill..." I would just accept that, even though I had a different experience and all these other people had a different experience. But I would throw that out because I thought my experience was an aberration.

Much of the early work focused on dopamine and we were really looking for rewarding sorts of effects and sure enough, we only found that. But you can destroy the main dopamine-producing structures of the brain and you can still get an animal to self-administer drugs like cocaine.

I've had investigations of my lab because people didn't like what I had to say. And when you have investigations and you're doing research, you're shut down for a while. You have to start all over again. So that's one area where I paid a high price.

One of the things that has happened is that our drug laws have been institutionalized now. If you want to say that somebody's a bad person in a movie or in a television show or something about that, you say they sell drugs or they use drugs.