As followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.

That our being should consist of two fundamental elements [physical and psychical] offers I suppose no greater inherent improbability than that it should rest on one only.

If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.

That a strong stimulus to such an afferent nerve, exciting most or all of its fibres, should in regard to a given muscle develop inhibition and excitation concurrently is not surprising.

As followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.

He solved at a stroke the great question of the direction of nerve-currents in their travel through brain and spinal cord.

Further study of central nervous action, however, finds central inhibition too extensive and ubiquitous to make it likely that it is confined solely to the taxis of antagonistic muscles.