If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
Charles Scott SherringtonThis integrative action in virtue of which the nervous system unifies from separate organs an animal possessing solidarity, an individual, is the problem before us.
Charles Scott SherringtonWith the nervous system intact the reactions of the various parts of that system, the 'simple reflexes', are ever combined into great unitary harmonies, actions which in their sequence one upon another constitute in their continuity what may be termed the 'behaviour'.
Charles Scott SherringtonThe terminal path may, to distinguish it from internuncial common paths, be called the final common path. The motor nerve to a muscle is a collection of such final common paths.
Charles Scott Sherrington