I think we're all guilty of mistaking the actors we've seen over and over again - we think we know them.

I don't think you should just do what makes you happy. Do what makes you great.

I never saw myself as a comedian. I saw myself as a guy who can act funny.

Knowing that I'm not a model and I'm never going to be has relieved me of the pressure of looking good. If you don't establish yourself as McDreamy then you don't have to live up to it.

Cats do not abide by the laws of nature.

As an actor, I think every moment in your life is giving you a new set of tools. You’re constantly absorbing new information that you can put back onto the screen.

You live your comedic life close to the edge, you're gonna cross the line and offend people.