It took a while for me to be able to sit in a room of studios and financiers and say, "I'm not some hoity-toity actress looking for a vanity deal - I really know how to make a film!" In order to do that, you've got to break your f-cking back.

I don't believe in charmed lives. I think that tragedy is part of the lesson you learn to lift yourself up, to pick yourself up and to move on.

Boys don't really like big nerdy glasses. Not so much.

Other than vaccines and finding a cure, most funding goes toward putting people on treatment. That's completely valid and I understand that, but it's never how we're going to stop AIDS.

It's pretty impossible to be a South African and not have been personally affected by HIV or AIDS.

You always have this fear in a movie of just being somebody's woman.

Men are like fine wines - the older they get, the better they get.