Other anatomical changes associated with long-duration space flight are definitely negative: the immune system weakens, the heart shrinks because it doesn't have to strain against gravity, eyesight tends to degrade, sometimes markedly (no one's exactly sure why yet). The spine lengthens as the little sacs of fluid between the vertebrae expand, and bone mass decreases as the body sheds calcium. Without gravity, we don't need muscle and bone mass to support our own weight, which is what makes life in space so much fun but also so inherently bad for the human body, long-term.
Chris HadfieldDoing a space walk. It is one of the most rare human experiences. To leave your spaceship and go outside, so that you are alone in the universe with Earth distant and the universe around you. That is amazing.
Chris HadfieldImbibe three or four times as much water as you think you need and skip at least one, if not two meals, when you are travelling. You should arrive at your destination feeling slightly hungry and your digestive system reset.
Chris HadfieldThe Nile, draining out into the Mediterranean. The bright lights of Cairo announce the opening of the north-flowing riverโs delta, with Jerusalemโs answering high beams to the northeast. This 4,258 mile braid of human life, first navigated end-to-end in 2004, is visible in a single glance from space.
Chris Hadfield