With an animated show you can make a banana purple. You can put three hats on a cowboy. That would require several days of stitching, in live-action, that you wouldn't be able to afford. I mean, you can just do tons and tons and tons.

If your ratings are high and there’s money being made, you’re allowed to be a perfectionist in television.

You have to just look at it like Titanic: I know the ship sinks, but this is a love story

Garry Shandling has always been a pioneer of… meta entertainment. He's always been a defender of the creative right to use the frame as part of the painting.

I am absolutely and inherently self-destructive in that I am always making sure I'm doing what I want to do.

None of us are bad people. We float around and we run across each other and we learn about ourselves, and we make mistakes and we do great things. We hurt others, we hurt ourselves, we make others happy and we please ourselves. We can and should forgive ourselves and each other for that.

I don't think it's going to be possible for the next generation of writers to tell stories without telling stories about telling stories.