Grief allows you to let go of something you have lost only when you begin to accept what you now have in its place. As our mind clings to the familiar, to our established expectations, we can become trapped in feelings of disappointment, confusion, anger, that create our own internal worlds of suffering.

Interpersonal experience shapes the mind as it continues to develop throughout the lifespan... Interactions with the environment, especially relationships with other people, directly shape the development of the brain's structure and function.

The number of possible "on-off" patterns of neuronal firing is immense, estimated as a staggering ten times ten one million times (ten to the millionth power). The brain is obviously capable of an imponderably huge variety of activity; the fact that it is often organized and functional is quite an accomplishment!

Each of us needs periods in which our minds can focus inwardly. Solitude is an essential experience for the mind to organize its own processes and create an internal state of resonance. In such a state, the self is able to alter its constraints by directly reducing the input from interactions with others. (p. 235)

Grief allows you to let go of something you have lost only when you begin to accept what you now have in its place. As our mind clings to the familiar, to our established expectations, we can become trapped in feelings of disappointment, confusion, anger, that create our own internal worlds of suffering.

Early experience shapes the structure and function of the brain. This reveals the fundamental way in which gene expression is determined by experience.

Internal mental experience is not the product of a photographic process. Internal reality is in fact constructed by the brain as it interacts with the environment in the present, in the context of its past experiences and expectancies of the future. At the level of perceptual categorizations, we have reached a land of mental representations quite distant from the layers of the world just inches away from their place inside the skull. This is the reason why each of us experiences a unique way of minding the world. (pp. 166-167)