I want to build a clock that ticks once a year. The century hand advances once every one hundred years, and the cuckoo comes out on the millennium. I want the cuckoo to come out every millennium for the next 10,000 years. If I hurry I should finish the clock in time to see the cuckoo come out for the first time.

I want to build a clock that ticks once a year. The century hand advances once every one hundred years, and the cuckoo comes out on the millennium. I want the cuckoo to come out every millennium for the next 10,000 years. If I hurry I should finish the clock in time to see the cuckoo come out for the first time.

A human body is a conversation going on, both within the cells and between the cells, and they're telling each other to grow and to die; when you're sick, something's gone wrong with that conversation.

Your genome knows much more about your medical history than you do.

Technology is everything that doesn’t work yet.

A novice was trying to fix a broken Lisp machine by turning the power off and on. Knight, seeing what the student was doing, spoke sternly: "You cannot fix a machine by just power-cycling it with no understanding of what is going wrong." Knight turned the machine off and on. The machine worked.

[Language is] really a pretty amazing invention if you think about it. Here I have a very complicated, messy, confused idea in my head. I'm sitting here making grunting sounds and hopefully constructing a similar messy, confused idea in your head that bears some analogy to it.