What is the thing that matters most to making progress right now?

Don't always worry about what your next line is supposed to be. There is no script. Live your life. Be in this moment.

Apple is our mentor, Facebook is our enemy.

Not only can you not plan the impact you're going to have, you often won't recognize it when you're having it.

Believe that if you make courageous choices, and bet on yourself, then you will have an impact.

If there's ever an example of the importance of making bold bets and focusing on what you love, it's Twitter.

The key is to just get on the bike, and the key to getting on the bike… is to stop thinking about ‘there are a bunch of reasons I might fall off’ and just hop on and peddle the damned thing. You can pick up a map, a tire pump, and better footwear along the way.