Why' is the only question that bothers people enough to have an entire letter of the alphabet named after it. The alphabet does not go 'A B C D What? When? How?' but it does go 'V W X Why? Z.

Zaphod did not want to tangle with them and, deciding that just as discretion is the better part of valor, so was cowardice is the better part of discretion, he valiantly hid himself in a closet.

I tend not to read or watch Science Fiction, particularly not comedy Science Fiction. The point is that if it's less good than what I do, there's no point in reading it, if it's better than what I do it makes me depressed

Anything invented before your fifteenth birthday is the order of nature. That's how it should be. Anything invented between your th and th birthday is new and exciting, and you might get a career there. Anything invented after that day, however, is against nature and should be prohibited.

If we see you smoking we will assume you are on fire and take appropriate action.

Did I do anything wrong today," he said, "or has the world always been like this and I've been too wrapped up in myself to notice?

Can't stand all these poisonous creatures, all these snakes and insects and fish and things. Wretched things, biting everybody. And then people expect me to tell them what to do about it. I'll tell them what to do. Don't get bitten in the first place. (quoting Dr. Struan Sutherland)