Unlike optogenetics, where there are existing nonprofits that give away the DNA for free or at cost, expansion microscopy requires chemicals to be used, so having a company that makes the chemistry kit that anybody can use can save time.

A big part of my job is to remember failure, and reboot failure, when the timing is right.

The brain is really hard to see. The whole thing is very large - the human brain is several pounds in weight - but the connections between brain cells, known as synapses, are really tiny. They're nanoscale in dimension. So if you want to see how the cells of the brain are connected in networks, you have to see those connections, those synapses.

I would argue that if you understand how the cells of the brain are organized into circuits, almost computational circuits if you will, and we see how information flows through those circuits and how it's transformed, we might have a much firmer grasp on why our brains make decisions the way that they do. If we get a handle on that, maybe we can overcome some of our limitations and at the very least we'll understand why we do what we do.

If our brain is understanding some parts of the universe and not understanding other parts, and those understandings are about the laws of physics that our brains are built on top of, then it's kind of a loop, right?

For the last century of neuroscience, lots of people have tried to control neurons using all sorts of different technologies - pharmacology (drugs), electrical pulses, and so on. But none of these technologies are precise. With optogenetics, we can aim light at a single cell, or a set of cells, and turn just that set of cells on or off.

If we succeed, it makes no sense to keep it only for ourselves.