Unfortunately, philosophers of science usually regard scientific realism and scientific anti-realism as monistic doctrines. The assumption is that there is one goal of all scientific inference - finding propositions that are true, or finding propositions that are predictively accurate. In fact, there are multiple goals. Sometimes realism is the right interpretation of a scientific problem, while at other times instrumentalism is.
Elliott SoberThe indispensability argument seeks to assimilate the epistemology of metaphysical statements to the epistemology of statements that are obviously empirical. I think it fails to achieve this goal. The argument does not refute the Carnapian thesis that scientific theories and metaphysical claims differ epistemologically - observations can provide evidence for the former, but not for the latter.
Elliott SoberCurrent organisms have a higher probability of sharing a single code if the common ancestry hypothesis is true than they'd have if the hypothesis of separate ancestry were true. That is, the simpler hypothesis has the higher likelihood in the technical sense of "likelihood" used in statistics.
Elliott Sober