A theory should not attempt to explain all the facts, because some of the facts are wrong

Christianity may be OK between consenting adults in private but should not be taught to young children.

In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.

Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.

How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.

Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.

For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.