You should always leave the party 10 minutes before you actually do.

The picture's pretty bleak, gentlemen... The world's climates are changing, the mammals are taking over, and we all have a brain about the size of a walnut.

I don't know where my ideas come from. I will admit, however, that one key ingredient is caffeine. I get a couple cups of coffee into me and weird things just start to happen.

On Career Day in high school, you don't walk around looking for the cartoon guy.

I think it's vital to be honest with yourself. You do have to satisfy yourself first. If you're drawing something, you have to ask yourself if it's something you genuinely think is funny. Or is it starting to fall into just a category, just kind of a shtick thing? I think it's important for all cartoonists to be honest with themselves about their own sense of humor and what they're doing.

I don't believe in the concept of hell, but if I did I would think of it as filled with people who were cruel to animals.

I never liked my own species. On why so many of his comics are about animals, in an interview.