Humans have changed ecosystems more rapidly and extensively than in any comparable period of time in human history, largely to meet rapidly growing demands for food, fresh water, timber, fiber and fuel. This has resulted in a substantial and largely irreversible loss in the diversity of life on Earth.

A long time ago, I became aware that many of us have a tendency to lump nature into simplistic categories, such as what we consider beautiful or ugly, important or unimportant. As human a thing as that is to do, I think it often leads us to misunderstand the respective roles of life forms and their interconnectedness.

You know those little snow globes that you shake up? I always thought my brain was sort of like that. You know, where you just give it a shake and watch what comes out and shake it again. It's like that.

Things can be low on the food chain, but that doesn't mean they're lowly.

By the time they had diminished from 50 to 8, the other dwarves began to suspect 'Hungry'.

I don't read cartoons because I think for the most part the comics don't have an interest for me. There's just nothing there these days that makes me want to go seek them out. I'm not trying to say my work wouldn't have sparked that same reaction from somebody else. There's just nothing there for me personally.

I never liked my own species. On why so many of his comics are about animals, in an interview.