When people have no interest in a subject, it's very hard to get them to laugh about it. If I had to write ten jokes about potholders, I don't think I could do it. But I could write ten jokes about Catholicism in the next twenty minutes.

You have to respect people's suffering. To deny that the world is unfair and painful for most of the people living in it would be false and judgmental.

I don't know what the universe is all about, but to me, nothing is gained by slapping a God sticker on it. It has never been a comfort to me to believe there's an all-seeing eye in the sky.

Men often struggle with their attraction to other women. They don't quite understand why they have to be with the same woman forever.

I don't like that The Simpsons are spokespeople for Burger King and MasterCard and Butterfinger. In the first Gulf War, I was really upset that the Simpsons characters were being drawn on tanks and bombs. But those are things that I don't control.

If there's reason for hope, it lies in man's occasional binges of cooperation. To save our planet, we'll need that kind of heroic effort, in which all types of people join forces for the common good

As a John Kerry supporter, I wanted to send him a check. But then it occurred to me that most of that money would end up in the hands of advertising agencies and television networks. And the money would be used to create deceptive commercials that flatter our point of view and shade the facts our way. And I wasn't comfortable with that. But on the other hand, that's how the game is played. You're always grappling.