When I was president of the company, I said, 'Okay, I can do this - piece of cake.' Then when you are the CEO, the responsibilities multiply enormously because you worry about everything.

The biological clock and the career clock are in total conflict with each other.

I don't think women can have it all. I just don't think so...My husband and I have been married for 34 years, and we have two daughters. And every day you have to make a decision about whether you are going to be a wife or a mother. In fact, many times during the day you have to make those decisions...We co-opted our families to help us. We plan our lives meticulously so we can be decent parents. But if you ask our daughters, I'm not sure they will say that I've been a good mom.

Whatever anybody says or does, assume positive intent.

At the end of the day, don't forget that you're a person.

When I grew up there was no web, blogging or tweeting. In fact, where I grew up there was not even television! I met a lot of my friends in school and in college, and they are still my friends today.

If you give up the guilt, that's a huge load off your shoulders.