I can calculate the motion of heavenly bodies, but not the madness of people.

If I have done the public any service, it is due to my patient thought.

God is able to create particles of matter of several sizes and figures and perhaps of different densities and forces, and thereby to vary the laws of nature, and make worlds of several sorts in several parts of the Universe.

Every action has an equal and opposite reaction

This thing is but a puny imitation of a much grander system whose laws you know, and I am not able to convince you that this mere toy is without a designer or maker; yet you profess to believe that the great original from which the design is taken has come into being without either designer or maker! Now tell me by what sort of reasoning do you reach such an incongruous conclusion?

I am ashamed to tell you to how many figures I carried these calculations [of Pi], having no other business at the time

Absolute, true and mathematical time, of itself, and from its own nature flows equably without relation to anything external.