Knowledge is not a loose-leaf notebook of facts. Above all, it is a responsibility for the integrity of what we are, primarily of what we are as ethical creatures.

I grew up to be indifferent to the distinction between literature and science, which in my teens were simply two languages for experience that I learned together.

The most remarkable discovery made by scientists is science itself. The discovery must be compared in importance with the invention of cave-painting and of writing. Like these earlier human creations, science is an attempt to control our surroundings by entering into them and understanding them from inside. And like them, science has surely made a critical step in human development which cannot be reversed. We cannot conceive a future society without science.

The great poem and the deep theorem are new to every reader, and yet are his own experiences, because he himself recreates them.

All those formal systems, in mathematics and physics and the philosophy of science, which claim to give foundations for certain truth are surely mistaken. I am tempted to say that we do not look for truth, but for knowledge. But I dislike this form of words, for two reasons. First of all, we do look for truth, however we define it, it is what we find that is knowledge. And second, what we fail to find is not truth, but certainty; the nature of truth is exactly the knowledge that we do find.

The symbol and the metaphor are as necessary to science as to poetry.

[John] Dalton was a man of regular habits. For fifty-seven years he walked out of Manchester every day; he measured the rainfall, the temperature-a singularly monotonous enterprise in this climate. Of all that mass of data, nothing whatever came. But of the one searching, almost childlike question about the weights that enter the construction of these simple molecules-out of that came modern atomic theory. That is the essence of science: ask an impertinent question, and you are on the way to the pertinent answer.