When systems are broken, it's an opportunity for invention and innovation.

Girls and women are most victimised in societies where boys and men are disempowered.

I was encouraged to break all the rules but to take the best of philanthropy, the best of investing, and the best of development finance, and experiment with new ways to create this venture capital model of using philanthropy to back patient capital investments, and then build solutions that were measured in terms of the kind of impact and change they were making on people's lives and in the world, not just on the financial return.

The only way we really create change is to enter any situation with the humility to listen and to recognize the world as it is, and then the audacity to dream what it could be.

We can send people to the Moon; we can see if there's life on Mars - why can't we get $5 [mosquito] nets to 500 million people?

I've heard it said that the most dangerous animal on the planet is the adolescent male.

There are cases where government-to-government aid actually has worked. Look at the eradication of smallpox and the near eradication of polio. But these are really top down solutions that require government-to-government support and aid.