It's a deep and all but certain truth about narcissistic personalities that to meet them is to love them, but to know them well is to find them unbearable. Confidence quickly curdles into arrogance; smarts turn to smugness, charm turns to smarm.

Toxins love to get you while you're young. Lead, mercury, secondhand smoke and sundry other environmental nasties do a lot more damage when tissue is immature, vulnerable and growing than when it's mature and comparatively fixed.

Spare a thought for the poor introverts among us. In a world of party animals and glad-handers, they're the ones who stand by the punch bowl. In a world of mixers and pub crawls, they prefer to stay home with a book. Everywhere around them, cell phones ring and e-mails chime and they just want a little quiet.

A close family member once offered his opinion that I exhibit the phone manners of a goat, then promptly withdrew the charge - out of fairness to goats.

There's plenty to read about keeping your sanity while raising children, but it's all common-sense stuff about task division and taking breaks and the relentlessly repeated magic of date night with your spouse. What's missing is some 'tude.

Credit or debit cards, for starters, are nothing short of shoppers' Novocain. Even in the age of digital purchases and virtual money, we still attach a special value to dirty paper with pictures of presidents on it. Handing some of that to a cashier simply hurts more than handing over a little sliver of plastic.

As MBA professors endlessly tell their students, companies do best when they stick to what they do well. There's a reason Apple doesn't make blenders. There's a reason Haagen-Dazs doesn't sell meat. And there's a reason drug companies should focus on saving and improving lives - not jeopardizing them.