Our ability to adapt came from our East African birthplace, a meteorologically unstable place. If you couldn't adapt, you'd be dead. But once you've found a solution, there is no need to continue the adaptive behavioral parrying, which is bioenergetically very expensive to maintain. We are built to find answers, then hang on to them as long as we can.

I have great confidence in human curiosity - even though I don't know what curiosity is from a biological point of view. One of its characteristics has got to be the willingness to explore.

Women tend to recall the details of an emotionally competent stimulus, using more of their left hemisphere to do the processing. Men tend to recall the gist aspects of an emotionally competent stimulus, using more of their right hemisphere to do the processing.

I think the most incredible fact about the brain is that it is the only piece of biological real estate that can actually study itself. I can think about that for decades - I have, actually - and still be in drop dead amazement.

You can practice for 30 years and still not be a Mozart. The most lethal combination would be a Mozart who practiced for thousands of hours.

There are estimates that we daily walked for 10 - 20 kilometers for hundreds of thousands of years. The world's best problem solving machinery grew up under conditions of consistent, strenuous physical activity. It makes sense that when we don't recreate the environments in which the organ was forged, we get a loss of function. And that when we do restore those environments, we get that function back. The effects of aerobic exercise on executive function skills is a powerful empirical example of this idea.

People try to apply directly results from the cognitive neurosciences directly to classroom practice and I have to tell you I am very skeptical about the exercise. We don't know very much about how the brain works - we don't even know how you remember to write your name.