If the Constitution says that the little guy should win, the little guy is going to win in court before me, ... But if the Constitution says that the big guy should win, well, then the big guy is going to win because my obligation is to the Constitution.

There are many different causes of the scarring. Viruses are common. Hepatitis B, hepatitis C, what we call autoimmune diseases where the body attacks the liver itself such as primary biliary cirrhosis is an autoimmune disease; sclerosing cholangitis is an autoimmune disease; and so those diseases where the liver is being destroyed by either the virus or an autoimmune disease, it can only scar, and why it doesn't regenerate has to do with the fact that there is this ongoing scar tissue that blocks that regeneration.

We are always in awe of what the donors have done in terms of providing of themselves to the recipients. It really is a heroic act because people take on themselves not only a risk of death but also pain-and-suffering in order for their loved one to get the benefit of the liver transplant.

Senator, my answer is that the independence and integrity of the Supreme Court requires that nominees before this committee for a position on that court not forecast, give predictions, give hints, about how they might rule in cases that might come before the Supreme Court,.

When we think about living donor transplant, what we're banking on is the ability of the liver to regenerate itself. Now, it's not the same sort of regeneration we think about with the starfish where we cut off the arm and it grows a new arm. With the liver, what happens is the remaining liver gets bigger, and your body knows the size of the liver that it needs, and when it recognizes that there is not enough liver, it sends nutrients and signals to the liver and says "get bigger."

End-stage liver disease refers to a liver that's failing, and a very high percentage of those livers are what we call cirrhotic, or the patient's liver has become cirrhotic, and what cirrhosis is, is the scarring of the liver tissue.

I'm not sure that it's right to view this as excluding a particular group. When the institution of marriage developed historically, people didn't get around and say, 'Let's have this institution, but let's keep out homosexuals.' The institution developed to serve purposes that, by their nature, didn't include homosexual couples.