You can bring together the body's various systems to fine tune the body and mind in order to navigate life's ups and downs in a way that minimizes stress and maximizes well-being and satisfaction.
Jon Kabat-ZinnWhen people say "Let it go," what they really mean is "Get over it," and that's not a helpful thing to say. It's not a matter of letting go - you would if you could. Instead of "Let it go," we should probably say "Let it be"; this recognizes that the mind won't let go and the problem may not go away, and it allows you to form a healthier relationship with what's bothering you.
Jon Kabat-ZinnSee If You Can Give Yourself Gifts That May Be True Blessings, Such As Self-Acceptance
Jon Kabat-ZinnTo let go means to give up coercing, resisting, or struggling, in exchange for something more powerful and wholesome which comes out of allowing things to be as they are without getting caught up in your attraction to or rejection of them, in the intrinsic stickiness of wanting, of liking and disliking.
Jon Kabat-Zinn