It is really irritating to work with irritating people

She looks at herself in the mirror. The idea is to look sexy again. And for whom exactly? Yourself, of course. Yes, well, that's all wonderfully self-affirming and very strong-minded as any decent woman should be these days, but let's just face facts here and say that when a woman - no, when a person is thinking about feeling sexy, it is always with the idea of someone else in mind.

Comedy is like fictional charm. It's the charm of fiction. Or the charisma of fiction. When you meet somebody who's immediately charismatic, you're attracted to that person. And in fiction it's got to come out in either one of two ways: in the prose itself, and you're hooked immediately because you never want to leave such a colorful and penetrating world. Or, it's simply being a funny writer.

The internet takes a lot of the anxiety of life away. It's a kind of deity. You're never lonely. You're always distracted. If you spend enough time on it, there's not really that nagging sensation of existential despair; it erases it very effectively. And it's monolithic. And thanks to it, we've got the ways to linger there after death - your blog exists afterwards, your e-mail exists afterwards.

There were times where I felt I was pressing a little bit too hard with the humor, and I had to pull back, because the overriding concern of the book was to create this disease that had no cure and make you pay attention to every emotional stage of what happens.

I'm being provided with some emotional ballast by giving me an intimate portrait of one character in particular in contrast to the collective. I'm fortunate that I had very sympathetic readers, but ordinarily - if a book makes you laugh too much, it shifts from "literature" to "entertainment."

Once I had the voice, I knew I wasn't going to fall off the bicycle. I tap right back into it. It really was like learning how to ride a bike - you never forget, and I was able to carry it along with some ease. I never encountered any stumping problems that left me not knowing what to do, so I was mostly able to hold my ground. Of course, I should mention that it took me a long time to actually acquire the voice; there were a lot of frustrated attempts along the way, revisions to long sections and versions of the book that I abandoned.