Everyone desires relationships and community. Most people want to belong to a cohesive, like-minded group. It staves off loneliness. It promotes identity. These are natural and very human instincts.

I wake up every day in order to do something that's quixotic, and not necessarily called for in the world, but I do it because there's extraordinary meaning for me behind the effort.

A child, thought Carl, is not the only result of childbirth. A mother, too, is born. You see them every day--nondescript women with a bulge just above the groin, slightly double-chinned. Perpetually forty. Someone's mother, you think. There is a child somewhere who has made this woman into a mother, and for the sake of the child she has altered her appearance to better play the part.

There were times where I felt I was pressing a little bit too hard with the humor, and I had to pull back, because the overriding concern of the book was to create this disease that had no cure and make you pay attention to every emotional stage of what happens.

The whole time I was writing, I had to fight my normal inclination to be funny, to sort of patch humor in, in order to convey all of the disruptions of the disease to the family dynamic, the loss of individuality, the impact on professional life, and the sanity of the main character. Of course, that's not to say it never sneaks in; there's some black comedy in there, like when he shows up to court wearing a bicycle helmet and won't take it off.

A dentist is only half the doctor he claims to be.

The people at the very top could fall by and grace you with their presence and give you a little largesse, and you'd be "Oh, I'm so beloved." In a way, it was kind of like flattery. The middle managers didn't quite have that cachet, but at the same time, they had to seem like they were of that caliber. So there's a little bit of loneliness at the heart of those with a little bit of power.