Others imply that they know what it is like to be depressed because they have gone through a divorce, lost a job, or broken up with someone. But these experiences carry with them feelings. Depression, instead, is flat, hollow, and unendurable. ... You're frightened, and you're frightening, and you're 'not at all like yourself but will be soon,' but you know you won't.

An ardent temperament makes one very vulnerable to dreamkillers.

In some cases, some people do get depressed in the middle of their grief and they really need to be treated for depression.

When I am high I couldn't worry about money of I tried. So I don't. The money will come from from somewhere; I am entitled; God will provide. Credit cards are disastrous, personal checks worse. Unfortunately, for manics anyway, mania is a natural extension of the economy.

Curiosity, wonder, and passion are defining qualities of imaginative minds and great teachers...Restlessness and discontent are vital things... Intense experience and suffering instruct us in ways less intense emotions can never do.

Without science, there would be no such hope.

When people are suicidal, their thinking is paralyzed, their options appear spare or nonexistent, their mood is despairing, and hopelessness permeates their entire mental domain. The future cannot be separated from the present, and the present is painful beyond solace. ‘This is my last experiment,’ wrote a young chemist in his suicide note. ‘If there is any eternal torment worse than mine I’ll have to be shown.