But in fact, when you try to model that on a computer you find that because of the very structure of matter and of the chemical bonds that are the basis of every organism, evolution is not random at all. It will tend to follow certain paths.

When a system is in turbulence, the turbulence is not just out there in the environment, but is a part of the organization or organism that you are looking at.

In a broad systems sense, an organism's environment is indistinguishable from the organism itself.

The current understanding was that it was impossible to predict how something would evolve because it was a very turbulent environment full of things interacting with each other.

Species go extinct because there are historical contraints built into a given body or a given design.

Managing bottom-up change is its own art.

Nobody is as smart as everybody.