Selfness is an essential fact of life. The thought of nonselfness, precise sameness is terrifying.

The human mind is not meant to be governed, certainly not by any book of rules yet written; it is supposed to run itself, and we are obliged to follow it along, trying to keep up with it as best we can.

The greatest achievements in the science of this [twentieth] century are themselves the sources of more puzzlement than human beings have ever experienced. Indeed, it is likely that the twentieth century will be looked back at as the time when science provided the first close glimpse of the profundity of human ignorance. We have not reached solutions; we have only begun to discover how to ask questions.

I have been trying to think of the earth as a kind of organism, but it is no go. I cannot think of it this way. It is too big, too complex, with too many working parts lacking visible connections. The other night, driving through a hilly, wooded part of southern New England, I wondered about this. If not like an organism, what is it like, what is it most like? Then, satisfactorily for that moment, it came to me: it is most like a single cell

Sometimes you get a glimpse of a semicolon coming, a few lines farther on, and it is like climbing a steep path through woods and seeing a wooden bench just at a bend in the road ahead, a place where you can expect to sit for a moment, catching your breath.

We are built to make mistakes, coded for error.

It is not so bad being ignorant if you are totally ignorant; the hard thing is knowing in some detail the reality of ignorance.