Exclamation points are the most irritating of all. Look! they say, look at what I just said! How amazing is my thought! It is like being forced to watch someone else's small child jumping up and down crazily in the center of the living room shouting to attract attention. If a sentence really has something of importance to say, something quite remarkable, it doesn't need a mark to point it out. And if it is really, after all, a banal sentence needing more zing, the exclamation point simply emphasizes its banality!

It hurts the spirit, somehow, to read the word environments, when the plural means that there are so many alternatives there to be sorted through, as in a market, and voted on.

Good applied science in medicine, as in physics, requires a high degree of certainty about the basic facts at hand, and especially about their meaning, and we have not yet reached this point for most of medicine.

If you want to use a cliche you must take full responsibility for it yourself and not try to fob it off on anon., or on society.

We are at our human finest, dancing with our minds, when there are more choices than two. Sometimes there are ten, even twenty different ways to go, all but one bound to be wrong, and the richness of the selection in such situations can lift us onto totally new ground.

The greatest achievements in the science of this [twentieth] century are themselves the sources of more puzzlement than human beings have ever experienced. Indeed, it is likely that the twentieth century will be looked back at as the time when science provided the first close glimpse of the profundity of human ignorance. We have not reached solutions; we have only begun to discover how to ask questions.

We're as clever as we think we are, but we'll be a lot cleverer when we learn to use not just one brain but to pool huge numbers of brains. We're at a level technologically where we can share information and think collectively about our problems. We do it in science all the time - there's no reason why we can't do it in other endeavors.