Science is the search for truth, that is the effort to understand the world: it involves the rejection of bias, of dogma, of revelation, but not the rejection of morality.

It was obvious-to me at any rate-that the answer was to why an enzyme is able to speed up a chemical reaction by as much as 10 million times. It had to do this by lowering the energy of activation-the energy of forming the activated complex. It could do this by forming strong bonds with the activated complex, but only weak bonds with the reactants or products.

Every aspect of the world today - even politics and international relations - is affected by chemistry.

...It would be possible to make much more progress than has been made if the NCI knew its job better, knew how to make discoveries...The NCI really does not know how to make discoveries....So long as the NCI is not willing to follow up ideas that seem good to people who have had experience making discoveries, the work of the NCI is going to be pedestrian.

Men will gather knowledge no matter what the consequences. Science will go on whether we are pessimistic or optimistic, as I am. More interesting discoveries than we can imagine will be made, and I am awaiting them, full of curiosity and enthusiasm.

During the time that [Karl] Landsteiner gave me an education in the field of imununology, I discovered that he and I were thinking about the serologic problem in very different ways. He would ask, What do these experiments force us to believe about the nature of the world? I would ask, What is the most. simple and general picture of the world that we can formulate that is not ruled by these experiments? I realized that medical and biological investigators were not attacking their problems the same way that theoretical physicists do, the way I had been in the habit of doing.

The McCarthy period came along...and many of the other scientists who had been working on these same lines gave up. Probably saying "Why should I sacrifice myself? I am a scientist, I am supposed to be working on scientific things, so I don't need to put myself at risk by talking about these possibilities." And I have said that perhaps I'm just stubborn... I have said "I don't like anybody to tell me what to do or to think, except Mrs. Pauling."