Activism that challenges the status quo, that attacks deeply rooted problems, is not for the faint of heart.

Nobody accomplishes success by themselves.

The iPod is clearly a tipping point (and I'm not quite sure it is a wholly positive development), because it is a revolution in the way that we consume creative property, which I would call art. It has radically changed the relationship between the artist and the audience, how money changes hands, and how much money changes hands. Music was the first, and books are coming next. The Kindle or some form of electronic book is clearly inevitable, and it will massively reshape how books are sold, who pays for them, and how they're consumed. It is going to be really fascinating.

People who bring transformative change have courage, know how to re-frame the problem and have a sense of urgency.

I worry that track is going to enter into an impossibly complicated stage, where our understanding of the complexities of human physiology - and our ability to accentuate and exploit them - is going to make the notion of pure competition impossible.

The Law of the Few... says that one critical factor in epidemics is the nature of the messenger.

The values of the world we inhabit and the people we surround ourselves with have a profound effect on who we are.