In this century, not only has science changed the world faster than ever, but in new and different ways. Targeted drugs, genetic modification, artificial intelligence, perhaps even implants into our brains - may change human beings themselves.

God invented space so that not everything had to happen in Princeton.

I suspect there could be life and intelligence out there in forms we can't conceive. Just as a chimpanzee can't understand quantum theory, it could be there as aspects of reality that are beyond the capacity of our brains They could be staring us in the face and we just Don't recognise them. The problem is that we-re looking for something very much like us, assuming that they at least have something like the same mathematics and technology.

Scientists habitually moan that the public doesn't understand them. But they complain too much: public ignorance isn't peculiar to science. It's sad if some citizens can't tell a proton from a protein. But it's equally sad if they're ignorant of their nation's history, can't speak a second language, or can't find Venezuela or Syria on a map.

An insect is more complex than a star..and is a far greater challenge to understand.

Indeed, our everyday world presents intellectual challenges just as daunting as those of the cosmos and the quantum, and that is where 99 per cent of scientists focus their efforts. Even the smallest insect, with its intricate structure, is far more complex than either an atom or a star.

In our interconnected world, novel technology could empower just one fanatic, or some weirdo with a mindset of those who now design computer viruses, to trigger some kind of disaster. Indeed, catastrophe could arise simply from technical misadventure - error rather than terror.