My age makes me think how valuable life is. How bad is something like Parkinson's in relation to not having life at all?

The purpose that you wish to find in life, like a cure you seek, is not going to fall from the sky. ...I believe purpose is something for which one is responsible; it's not just divinely assigned.

They did something once that slurred my speech, and I thought, "Oh, man, you're messing with my brain. It's freaking me out."

I have no argument with those who see in organized religion a template or an imperative to live life according to a prescribed set of beliefs. Just give others the room, within the laws of civil society, to believe or not believe whatever they like.

When I started it [non for profit], I thought, I'm not smart enough to do this. I had no experience in management, no experience in administration, no experience in nonprofit; but then this phrase came into my head: I only have to be smart enough to find people who are smarter than me; I only have to be smart enough to recognize who knows more than me.

People want leadership, Mr. President, and in the absence of genuine leadership, they'll listen to anyone who steps up to the microphone. They want leadership. They're so thirsty for it they'll crawl through the desert toward a mirage, and when they discover there's no water, they'll drink the sand.

Life is good, and there's no reason to think it won't be--right up until the moment when everything explodes into a fireball of tiny, unrecognizable fragments, or it all goes skidding sideways, through the guardrail, over the embankment, and down the mountain. This will happen (and probably more than once).