Artificial selection turned the wolf into the shepherd, and the wild grasses into wheat and corn. In fact, almost every plant and animal that we eat today was bred from a wild, less edible ancestor. If artificial selection can work such profound changes in only ten or fifteen thousand years, what can natural selection do operating over billions of years? The answer is all the beauty and diversity of life.

We think scientific literacy flows out of how many science facts can you recite rather than how was your brain wired for thinking. And it's the brain wiring that I'm more interested in rather than the facts that come out of the curriculum or the lesson plan that's been proposed.

You could be a poet, an artist, a comedian - if you're in the culture of innovation then you embrace those who do and you're going to protect the science curriculum in the classroom because you understand the meaning and the value of it. And science discoveries don't scare you. You say, "Give me more science", not less. "Give me more technology", not less.

I'm optimistic. I see no longer people accepting fuzzy thinking in the world. The change is not that people aren't still saying under-informed things. The change is that if you're in power and you say something under-informed, there are people out there with a voice who will take you to task for having done so

In whatever you choose to do, do it because it's hard, not because it's easy. Math and physics and astrophysics are hard. For every hard thing you accomplish, fewer other people are out there doing the same thing as you. That's what doing something hard means. And in the limit of this, everyone beats a path to your door because you're the only one around who understands the impossible concept or who solves the unsolvable problem.

Never presume that just because you disagree with an idea that you must be correct.

To get an Emmy nomination for a show that was the first-ever science talk show on television to us was an affirmation that there is an appetite for this content in the mainstream public, not just the erudite public. So we're all completely thrilled by it.