People sometimes mistake being serious with being taken seriously.

I did a play called 'On Golden Pond' in a dinner theater in Maine and then went to New York for a talent competition having put together a three-man juggling routine and some one-liners and I got myself an agent from that

My big thing is to make sure the lipsticks taste good when you kiss. And, well, so far they taste pretty darn good.

Oh, she's my bodyguard. I mean, I'm a married man, and the last thing you need in that situation is to be considered a sexy individual. But I try to never let this whole McDreamy thing really influence us. I'm trying to just have a calm family life, to make my marriage work. It's not as if when my wife asks me to take out the trash, I say, 'Um, honey, don't you realize that I'm too sexy for that'? Well, actually, I do, but she gives me crap for it.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

The hardest thing about having three kids is trying to find a balance, because there's always the odd man out, and you also need to make sure each child gets the attention he or she needs.

You'll go insane if you try to have a picture-book house.