"Nuclear" is nothing but trouble. Do you say "new-clear" or do you say "nuke-you-ler"? Whoever invented that word had obviously never studied the human mouth. We don't have enough muscles in our face to make that group of letters come out smoothly. The word is missing a middle syllable, for cryin' out loud.

I think things go wrong when there's not a very specific plan and specific emotional roadmap. You need to know what a scene needs to get across, and what story point that needs to be advanced, whether it's discovering someone for the first time or whether it's seeing a relationship get strained. What I do as a director is really create a safe environment that everyone can feel very comfortable in and experiment within so that they don't hold back anything.

The reason most comedies don't win awards is that the filmmakers put the comedy first. This means you have to create a story around the jokes.

What I don't like is when I see stuff that I know has had a lot of improv done or is playing around where there's no purpose to the scene other than to just be funny. What you don't want is funny scene, funny scene, funny scene, and now here's the epiphany scene and then the movie's over.

One of the biggest things you have is your reputation and your reputation with knowing what's good and what's not good.

I hate that we're always called "the all-female Ghostbusters," because you wouldn't refer to the original as "the all-male Ghostbusters."

My wife and I don't have kids and people are down on us about it. But we're just not wired that way, so don't tell me I have to.