I really do think for the vast majority of cases, doctors didn't think they were doing anything wrong - they were doing what was being recommended at the time, and many times people were able to take these prescription opioids and not have a problem with it. But what we do know is that if we take these drugs long-term, dependency develops quickly, within as little as a week. What we all have to realize is that these pills are chemical cousins of heroin - one is an illegal opioid and one is legal, but they are relatives.

In 1999, Purdue Pharma the maker of OxyContin went on a massive marketing campaign. Back then, prescription opioids were only used in extreme cases - post surgery, end of life care, cancer pain. We use a clip from an ad in the film where they had a doctor saying, "Less than 1 percent of people who use prescription opioid long-term will become addicted" - that changed the mindset of physicians across the country.

Addiction is a brain disease - this isn't a moral failing - and we have got to stop looking at it that way.

There seems is predominantly a white person's drug addiction epidemic, so that's why you see white people in our film, Warning: This Drug May Kill You.

Life expectancy for middle-aged white women has dropped dramatically over the past decade. Researchers didn't understand what was going on and so they were studying it and then very recently they realized it is driven by opioids. Why is that? They say now that it is because women are more likely to see a doctor for pain.

I want to make it clear, though, that I am not trying to say these are bad drugs. Opioid medications in the short term for severe pain are very effective. The problem is when they are used for long-term chronic pain. No one wants anyone to suffer and be in pain. But realize how addictive these drugs are and get off of them as quickly as you can. So 'Warning: This Drug May Kill You' is really more about educating people about these drugs so that everyone can make their own decision about their pain versus the addictive nature of these drugs.

I really do think for the vast majority of cases, doctors didn't think they were doing anything wrong - they were doing what was being recommended at the time, and many times people were able to take these prescription opioids and not have a problem with it. But what we do know is that if we take these drugs long-term, dependency develops quickly, within as little as a week. What we all have to realize is that these pills are chemical cousins of heroin - one is an illegal opioid and one is legal, but they are relatives.