I really do think for the vast majority of cases, doctors didn't think they were doing anything wrong - they were doing what was being recommended at the time, and many times people were able to take these prescription opioids and not have a problem with it. But what we do know is that if we take these drugs long-term, dependency develops quickly, within as little as a week. What we all have to realize is that these pills are chemical cousins of heroin - one is an illegal opioid and one is legal, but they are relatives.

We can prevent more people from becoming more addicted - that's number one - with prescribing laws and making sure that people can't get too many of these opioids when they are initially prescribed them. Number two is, we have to make sure the millions of people who are already addicted have access to good and effective treatment. Finally, it's critical that we remove stigma and that's why we've made a film, to show that this can happen to anyone.

It seemed that the problem of Americans overdosing and dying from drug addiction was being described as bad people, particularly kids, who were abusing good drugs. But Sheila Nevins, the president of HBO Documentary Films, and I were particularly interested in finding out the stories of people and families who had been ravaged by this disease of addiction and understanding what really was happening. What we found was that, and let's not make any mistake about it, this is an epidemic of addiction.

There seems is predominantly a white person's drug addiction epidemic, so that's why you see white people in our film, Warning: This Drug May Kill You.

We are having a public health response to this epidemic of prescription opioids. We are looking at treatment options, there are drugs being made available for treatments, and we aren't just throwing people in prison. So this is a very different response than the traditional criminal justice response that we have had to past drug epidemics.

I hope 'Warning: This Drug May Kill You' documentary helps to show the humanity of the people who are struggling with the brain disease of addiction because that is what this is - this isn't about bad people, this is about good people who became addiction oftentimes in the process of being prescribed medication for pain.

We did decide that every addict in this film, Warning: This Drug May Kill You, would be someone who started out with a prescription for an opioid from a doctor. The story that hadn't been told is that the vast majority - somewhere around 80 percent - of current heroin users began with an addiction to prescription opioids. So as much as people might want to look at this and say, 'Oh this is really a heroin problem,' yes, it is a heroin problem, and no one is saying differently, but it starts more often than not with a prescription.