You should command and demand the tenfold leverage on your dollars when you give it away as well.

I became very much, if I have to describe myself, I'm sort of a Libertarian Capitalist, and I was looking for, what's the economic engine that's going to drive us into space?

You've got to choose your horse ahead of time. So, if you're interested in water technology, energy technology, you get to choose between the three or four companies that you have insight into. And you have to make a bet on them before they prove anything out.

You have to ask yourself the question, do you have the smartest people in the world working for your company? And if you do, you're lucky. But if you don't, put up the incentive. And have someone who is absolutely brilliant who's a 22-year old in India who says what about this way? And who revolutionizes the way you do business.

By 2020 the U.S. will be short 91,000 doctors. There's no way we can educate enough doctors to make up that shortfall, and other countries are far worse off.

If someone is always to blame, if every time something goes wrong someone has to be punished, people quickly stop taking risks. Without risks, there can't be breakthroughs.

More than ever before in history, individuals can now band together to solve grand challenges. We face enormous problems, but we 'as individuals' have enormous power to solve them.