The world's biggest problems are the world's biggest business opportunities.

You have to ask yourself the question, do you have the smartest people in the world working for your company? And if you do, you're lucky. But if you don't, put up the incentive. And have someone who is absolutely brilliant who's a 22-year old in India who says what about this way? And who revolutionizes the way you do business.

If the risk is fully aligned with your purpose and mission, then it's worth considering.

The best way to become a billionaire is to help a billion people.

In 1980, during my sophomore year at MIT, I realized that the school didn't have a student space organization. I made posters for a group I called Students for the Exploration and Development of Space and put them up all over campus. Thirty-five people showed up. It was the first thing I ever organized, and it took off!

What is grit? Grit is refusing to give up. It's persistence. It's making your own luck.

More than ever before in history, individuals can now band together to solve grand challenges. We face enormous problems, but we 'as individuals' have enormous power to solve them.