I think in life the key thing is just to fight really hard to make sure something survives. If it looks like you've done everything you can to avoid failure, just move forward, move on and learn from it.

Global warming is another big area that we need to get on top of. And diseases in Africa, which we're also working on and seeing if we can make a difference on. And there are lots of issues that governments seem to be blind about.

Don’t just play the game – change it for good.

You get the idea. Every business, like a painting, operates according to its own rules. There are many ways to run a successful company. What works once may never work again. What everyone tells you never to do may just work, once. There are no rules. You don't learn to walk by following rules. You learn by doing, and by falling over, and it's because you fall over that you learn to save yourself from falling over. It's the greatest thrill in the world and it runs away screaming at the first sight of bullet points.

If you get into entrepreneurshi p driven by profit, you are a lot more likely to fail. The entrepreneurs who succeed usually want to make a difference to people’s lives, not just their own bank balances. The desire to change things for the better is the motivation for taking risks and pursuing seemingly impossible business ideas.

We had an electrical fault about 500 miles into the trip and lost more than half our fuel. We had a fire on the roof. And missed Los Angeles by 3,500 miles at the end of the trip and ending up in the arctic in a snowstorm.

And you know, I've had great fun turning quite a lot of different industries on their head and making sure those industries will never be the same again, because Virgin went in and took them on.