If you don't work on important problems, it's not likely that you'll do important work.

Knowledge and productivity are like compound interest. The more you know, the more you learn; the more you learn, the more you can do; the more you can do, the more the opportunity. I don`t want to give you a rate, but it is a very high rate. Given two people with exactly the same ability, the one person who manages day in and day out to get in one more hour of thinking will be tremendously more productive over a lifetime.

If the prior distribution, at which I am frankly guessing, has little or no effect on the result, then why bother; and if it has a large effect, then since I do not know what I am doing how would I dare act on the conclusions drawn?

The real problem is what can man and machine do together and not in competition.

Given two people with exactly the same ability, the one person who manages day in and day out to get in one more hour of thinking will be tremendously more productive over a lifetime.

One of the characteristics of successful scientists is having courage.

Science is concerned with what is possible while engineering is concerned with choosing, from among the many possible ways, one that meets a number of often poorly stated economic and practical objectives.