Depression is not generalized pessimism, but pessimism specific to the effects of one's own skilled action.

Almost always, genes are about potentials and vulnerabilities rather than about determinism.

...I might continue to believe that there is no god even if it were proved that there is. A religious friend of mine once remarked that the concept of god is useful, because you can berate god during the bad times. But it is clear to me that I don't need to believe there is a god in order to berate him.

There's the complex categorization of low warmth/high competence. This is the hostile stereotype of Asian Americans by white America, of Jews in Europe, of Indo-Pakistanis in East Africa, of Lebanese in West Africa, of ethnic Chinese in Indonesia, and of the rich by the poor most everywhere. It's the same low-high derogation: They're cold, greedy, clannish - -but, dang, they're sure good at making money and you should go to one who is a doctor if you're seriously sick.

Digestion is quickly shut down during stress…The parasympathetic nervous system, perfect for all that calm, vegetative physiology, normally mediates the actions of digestion. Along comes stress: turn off parasympathetic, turn on the sympathetic, and forget about digestion.

Some Poor grad student pressing on the flanks of a hamster and out comes a doctorate on the other side

Finish this lecture, go outside, and unexpectedly get gored by an elephant, and you are going to secrete glucocorticoids. There's no way out of it. You cannot psychologically reframe your experience and decide you did not like the shirt, here's an excuse to throw it out - that sort of thing.